Image Analysis

Areas of Image Analysis Expertise

  • Cardiovascular
    • cardiac LV/RV analysis from ultrasound and RT3DE
    • endothelial function from ultrasound
    • intimal-medial thickness from ultrasound
    • aortic analysis in 3D/4D from CT and MR
    • coronary plaque morphology
    • virtual histology (IVUS)
    • angiography/IVUS/OCT data fusion - geometrically correct reconstruction
    • aortic thrombus analysis
    • aneurysm morphology and biomechanics
    • computational fluid dynamics - wall sheer stress
    • plaque staging and progression analyses
  • Pulmonary
    • lungs
    • lung lobes
    • airway trees
    • vascular trees
    • artery-vein separation
    • pulmonary fissures
    • pulmonary parenchyma
    • bronchoscopy biopsy guidance
    • computational fluid dynamics - pulmonary airflow
    • particle deposition and tracking
    • COPD assessment, global and regional
  • Ophthalmic
    • fundus photography
    • fundus-photo based screening
    • retinal OCT - layers, fluid-filled abnormalities
    • cornea
    • visual function from structure
    • murine OCT
  • Orthopaedic
    • trabecular bone
    • cartilage
    • biomechanics
  • Neuroscience
  • Cancer
    • tumor analysis and staging
    • multi-modality analyses
    • multi-scale analyses
    • treatment outcome predictions
    • radiation treatment delivery
  • Small animal
    • registration
    • pulmonary analyses
    • cardiovascular analyses
    • tumor analyses

General-purpose image analysis methodologies

  • Image registration
    • rigid
    • non-rigid
    • inverse consistent
  • Image segmentation
    • LOGISMOS family of graph-based image segmentation approaches
    • Cost function design
      • edge based
      • region based
      • edge and region combined
      • automated design from segmentation examples
    • Fuzzy connectivity approaches
    • Level-set approaches
  • Mathematical morphology and digital geometry
  • Texture analysis
  • Tissue analysis
  • Just-enough-interaction (JEI) image segmentation refinement
    • semi-automated refinement of LOGISMOS-based image segmentations
  • Large-scale image analysis for clinical trials
    • brain
    • lung
    • cardiac
    • ophthalmic
    • vascular
  • Disease progression and treatment outcome prediction
    • coronary plaque
    • retinal AMD
    • cancer and cancer treatment
  • Radiation treatment delivery
    • IMRT optimization
    • tumor & lymph node tissue characterization
  • Translation of research results to commercial use